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Smith Predictor Sliding Mode Closed-loop Glucose Controller in Type 1 Diabetes
Universidad de Gerona.
KTH, School of Electrical Engineering (EES), Automatic Control. (Automatic Control Laboratory)
2011 (English)In: Proceedings of the 18th IFAC World Congress, 2011, 2011Conference paper (Refereed)
Abstract [en]

Type 1 diabetic patients depend on external insulin delivery to keep their blood glucose within near-normal ranges. In this work, two robust closed-loop controllers for blood glucose control are developed to prevent the life-threatening hypoglycemia, as well as to avoid extended hyperglycemia. The proposed controllers are designed by using the sliding mode control technique in a Smith predictor structure. To improve meal disturbance rejection, a simple feedforward controller is added to inject meal-time insulin bolus. Simulation studies were used to test the controllers, and shown the controllers ability to regulate the blood glucose within the safe limits in the presence of errors in measurements, modeling, and meal estimation.

Place, publisher, year, edition, pages
Keyword [en]
Type 1 diabetes Mellitus, glucose closed-loop control, Smith predictor
National Category
Control Engineering
URN: urn:nbn:se:kth:diva-46981DOI: 10.3182/20110828-6-IT-1002.01213ScopusID: 2-s2.0-84866749007OAI: diva2:454396
18th IFAC World Congress. Milano, Italy.
QC 20111108Available from: 2011-11-07 Created: 2011-11-07 Last updated: 2011-11-08Bibliographically approved

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