On-Chip Liquid Degassing With Low Water Loss
2010 (English)In: Proceedings Micro Total Analysis Systems (μTAS) 2010, Groningen: CBMS , 2010, 1790-1792 p.Conference paper (Refereed)
We present a novel approach for actively degassing liquid and removing trapped air bubbles in microfluidic devices.
In our approach, an integrated gas permeable membrane, consisting of a structurally supporting PDMS layer that is covered with a thin Teflon® AF 1600 film, separates the on-chip liquid from an on-chip low-vacuum chamber. Since the Teflon AF permeability is near zero for liquid water and low for vapour, air bubbles and dissolved air are removed through the membrane whilst the loss of water, ions and biomolecules in the system remains low. The system has been demonstrated at elevated temperatures and could be suitable for e.g. degassing during on-chip PCR.
Place, publisher, year, edition, pages
Groningen: CBMS , 2010. 1790-1792 p.
Debubbling, Teflon AF 1600, Selective Membrane, On-Chip Polymerase Chain Reaction
Engineering and Technology
IdentifiersURN: urn:nbn:se:kth:diva-48368ScopusID: 2-s2.0-80052135407ISBN: 978-0-9798064-3-8OAI: oai:DiVA.org:kth-48368DiVA: diva2:457436
14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 3 - 7 October 2010, Groningen, The Netherlands
QC 201111182011-11-182011-11-172015-10-26Bibliographically approved