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On-Chip Liquid Degassing With Low Water Loss
KTH, School of Electrical Engineering (EES), Microsystem Technology (Changed name 20121201).
KTH, School of Electrical Engineering (EES), Microsystem Technology (Changed name 20121201).ORCID iD: 0000-0002-0441-6893
KTH, School of Electrical Engineering (EES), Microsystem Technology (Changed name 20121201).ORCID iD: 0000-0001-6443-878X
KTH, School of Electrical Engineering (EES), Microsystem Technology (Changed name 20121201).ORCID iD: 0000-0001-9552-4234
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2010 (English)In: Proceedings Micro Total Analysis Systems (μTAS) 2010, Groningen: CBMS , 2010, 1790-1792 p.Conference paper, Published paper (Refereed)
Abstract [en]

We present a novel approach for actively degassing liquid and removing trapped air bubbles in microfluidic devices.

In our approach, an integrated gas permeable membrane, consisting of a structurally supporting PDMS layer that is covered with a thin Teflon® AF 1600 film, separates the on-chip liquid from an on-chip low-vacuum chamber. Since the Teflon AF permeability is near zero for liquid water and low for vapour, air bubbles and dissolved air are removed through the membrane whilst the loss of water, ions and biomolecules in the system remains low. The system has been demonstrated at elevated temperatures and could be suitable for e.g. degassing during on-chip PCR.

Place, publisher, year, edition, pages
Groningen: CBMS , 2010. 1790-1792 p.
Keyword [en]
Debubbling, Teflon AF 1600, Selective Membrane, On-Chip Polymerase Chain Reaction
National Category
Engineering and Technology
Identifiers
URN: urn:nbn:se:kth:diva-48368Scopus ID: 2-s2.0-80052135407ISBN: 978-0-9798064-3-8 (print)OAI: oai:DiVA.org:kth-48368DiVA: diva2:457436
Conference
14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 3 - 7 October 2010, Groningen, The Netherlands
Note

QC 20111118

Available from: 2011-11-18 Created: 2011-11-17 Last updated: 2015-10-26Bibliographically approved

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Haraldsson, TommySandström, NiklasStemme, GöranWijngaart, Wouter van der

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Karlsson, J. MikaelHaraldsson, TommySandström, NiklasStemme, GöranRussom, AmanWijngaart, Wouter van der
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