A phase code for memory could arise from circuit mechanisms in entorhinal cortex
2009 (English)In: Neural Networks, ISSN 0893-6080, E-ISSN 1879-2782, Vol. 22, no 8, 1129-1138 p.Article in journal (Refereed) Published
Neurophysiological data reveals intrinsic cellular properties that suggest how entorhinal cortical neurons could code memory by the phase of their firing. Potential cellular mechanisms for this phase coding in models of entorhinal function are reviewed. This mechanism for phase coding provides a substrate for modeling the responses of entorhinal grid cells, as well as the replay of neural spiking activity during waking and sleep. Efforts to implement these abstract models in more detailed biophysical compartmental simulations raise specific issues that could be addressed in larger scale population models incorporating mechanisms of inhibition.
Place, publisher, year, edition, pages
PERGAMON-ELSEVIER , 2009. Vol. 22, no 8, 1129-1138 p.
MEDIAL TEMPORAL-LOBE, FREELY MOVING RATS, LAYER-II NEURONS, HIPPOCAMPAL PLACE CELLS, TO-SAMPLE TASK, GRID CELLS, EPISODIC MEMORY, WORKING-MEMORY, THETA-RHYTHM, SUBTHRESHOLD OSCILLATIONS
Neurosciences Bioinformatics (Computational Biology)
IdentifiersURN: urn:nbn:se:kth:diva-50982DOI: 10.1016/j.neunet.2009.07.012ISI: 000271175800010PubMedID: 19656654OAI: oai:DiVA.org:kth-50982DiVA: diva2:463147
QC 201112122011-12-082011-12-082011-12-12Bibliographically approved