A system to quantify and visualize ventricular rotation pattern of the heart
2009 (English)Patent (Other (popular science, discussion, etc.))
Different modalities have been used to describe the rotational motion of the ventricles of the heart and studies have indicated LV twist to be an additional integral component in LV function. So far, only amplitudes and timings of rotation have been reported, whereas no method is available to fully describe the rotation pattern of the ventricles. The object of the present application is to achieve a system that presents a novel way to quantify and visualize the ventricular rotation pattern of the heart. We present a novel method that assesses and describes the rotation pattern by calculating the rotation axis of the ventricle. Non- invasive image acquisition is required to collect rotation values from different positions of the myocardium. Thereafter, a kinematic model of a ventricle is constructed to determine the rotation planes at different levels of the heart. The motion of the rotation planes are visualized by plotting the normal vectors of the planes over time, i.e. the rotation axis of the planes. This new method is different to all other methods used today for assessing cardiac function, as it does not describe the amplitude of a motion but the relationship in motion between different parts within a ventricle. Preliminary results indicate that the rotation axis is more sensitive to changes in the rotation pattern than conventional measurements of ventricular rotation. This new method could be used for early detection of cardiac diseases and for selection of patients for and optimization of cardiac resynchronization therapy.
Place, publisher, year, edition, pages
IdentifiersURN: urn:nbn:se:kth:diva-51354OAI: oai:DiVA.org:kth-51354DiVA: diva2:463961
SE 534636 (2011-11-01)
QC 20111212. QC 201308062011-12-122011-12-122013-08-06Bibliographically approved