Modeling of plasticity of the synaptic connections in the lamprey spinal CPG - consequences for network behavior
2000 (English)In: Neurocomputing, ISSN 0925-2312, Vol. 32-33, 441-446 p.Article in journal (Refereed) Published
Consequences of synaptic plasticity in the lamprey spinal CPG are analyzed. This is motivated by the experimentally found effects substance P and 5-hydroxytryptamin (5-HT) have on the inhibitory and excitatory synaptic transmission. The effects can be a change of the amplitude of the postsynaptic potentials as well as induction of an activity-dependent facilitation or depression during repetitive activation. Simulations show that network level effects (i.e. swimming frequency) of substance P and 5-HT can to a substantial part be explained based on their effects on the plasticity of the synaptic transmission.
Place, publisher, year, edition, pages
2000. Vol. 32-33, 441-446 p.
Central pattern generator; Lamprey; Locomotion; Synaptic plasticity
Computer and Information Science
IdentifiersURN: urn:nbn:se:kth:diva-58743DOI: http://dx.doi.org/10.1016/S0925-2312(00)00197-1OAI: oai:DiVA.org:kth-58743DiVA: diva2:473875
NR 201408052012-01-082012-01-08Bibliographically approved