Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
A physiological study of the monosynaptic reflex responses of cat spinal alpha-motoneurons after lumbusacral deafferentation
KTH, School of Computer Science and Communication (CSC), Computational Biology, CB.ORCID iD: 0000-0002-0550-0739
1989 (English)In: Brain Research, ISSN 0006-8993, E-ISSN 1872-6240, Vol. 488, 149-162 p.Article in journal (Refereed) Published
Abstract [en]

In adult cats the whole S1 and rostral half of the L7 dorsal roots were cut on the left side of the spinal cord to produce a partial monosynaptic deafferentation of the ipsilateral alpha-motoneurons. Three, 6 or 12 weeks later, monosynaptic reflexes (MSRs) were recorded from the L6, L7 and S1 ventral roots or from various peripheral nerves during stimulation of the L6 and remaining parts of the L7 dorsal roots. Also, monosynaptic excitatory postsynaptic potentials (EPSPs) were recorded intracellularly in different types of medial gastrocnemius alpha-motoneurons of the L7 segment during stimulation of various hind limb muscle nerves. The right side with an identical acute deafferentation served as control. On the chronically lesioned side the MSRs were increased in size, also during post-tetanic potentiation. The monosynaptic EPSPs had increased amplitudes in all motoneuron types, but the relation in EPSP size between different motoneuron types as well as between different synergistic inputs remained largely unchanged. EPSP rise times were not changed, and aberrant monosynaptic connections from non-synergist muscles were not observed. It is concluded that the extent of reactive reflex changes may be related to both the number of vacant synaptic sites and the degree of functional synergism between the eliminated and remaining monosynaptic pathways. Possible underlying mechanisms are discussed.

Place, publisher, year, edition, pages
1989. Vol. 488, 149-162 p.
National Category
Computer and Information Sciences
Identifiers
URN: urn:nbn:se:kth:diva-58752OAI: oai:DiVA.org:kth-58752DiVA: diva2:473936
Note
NR 20140805Available from: 2012-01-08 Created: 2012-01-08 Last updated: 2018-01-12Bibliographically approved

Open Access in DiVA

No full text

Authority records BETA

Hellgren Kotaleski, Jeanette

Search in DiVA

By author/editor
Hellgren Kotaleski, Jeanette
By organisation
Computational Biology, CB
In the same journal
Brain Research
Computer and Information Sciences

Search outside of DiVA

GoogleGoogle Scholar

urn-nbn

Altmetric score

urn-nbn
Total: 39 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf