Bacterial display in directed evolution for generation of new biopharmaceuticals
2011 (English)In: Biotech International, ISSN 2032-2887, Vol. 23, no June, 26-29 p.Article in journal (Other academic) Published
The successful use of monoclonal antibodies and antibody derivatives for therapeutic and in vivo diagnostic applications has resulted in a rapid progression in the fields surrounding biopharmaceutical drug discovery and combinatorial protein engineering. Consequently, investigations on new and improved technologies for both generation and characterisation of specific antibodies and alternative protein scaffolds are continuously being reported in the literature. This review summarises the recent efforts in development and application of bacterial display platforms for such purposes.
Place, publisher, year, edition, pages
2011. Vol. 23, no June, 26-29 p.
Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)
IdentifiersURN: urn:nbn:se:kth:diva-60010OAI: oai:DiVA.org:kth-60010DiVA: diva2:477078
QC 201201302012-01-122012-01-122012-01-30Bibliographically approved