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Estimating the distribution of the G2 phase duration from flow cytometric histograms
Lund University.
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2008 (English)In: Mathematical Biosciences, ISSN 0025-5564, E-ISSN 1879-3134, Vol. 211, no 1, 1-17 p.Article in journal (Refereed) Published
Abstract [en]

A mathematical model, based on branching processes, is proposed to interpret BrdUrd DNA FCM-derived data. Our main interest is in determining the distribution of the G(2) phase duration. Two different model classes involving different assumptions on the distribution of the G(2) phase duration are considered. Different assumptions of the G(2) phase duration result in very similar distributions of the S phase duration and the estimated means and standard deviations of the G(2) phase duration are all in the same range.

Place, publisher, year, edition, pages
2008. Vol. 211, no 1, 1-17 p.
Keyword [en]
branching process, cell cycle progression, G(2) phase duration, flow cytometry
National Category
Probability Theory and Statistics Cell Biology
Identifiers
URN: urn:nbn:se:kth:diva-61486DOI: 10.1016/j.mbs.2007.08.009ISI: 000253029900001PubMedID: 17942127OAI: oai:DiVA.org:kth-61486DiVA: diva2:479225
Note
QC 20120118Available from: 2012-01-17 Created: 2012-01-17 Last updated: 2017-12-08Bibliographically approved

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