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Method for enhancing the immunogenicity of an immunogenic compound or hapten, and use thereof for preparing vaccines
KTH, Superseded Departments, Biotechnology. (Nygren)ORCID iD: 0000-0003-4214-6991
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1994 (English)Patent (Other (popular science, discussion, etc.))
Abstract [en]

The present invention relates to a process for improving the immunogenicity of an immunogen, an antigen or a hapten, when it is administered to a host, independently of the mode of administration, characterized in that the said antigen or hapten is coupled covalently to a support molecule in order to form a complex, and in that this support molecule is a polypeptide fragment which is able to bind specifically to mammalian serum albumin. The invention also relates to the use, as a medicament, of the product which can be obtained in this way.

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Medical and Health Sciences
URN: urn:nbn:se:kth:diva-70213OAI: diva2:486078
FR 2726471B1 (1997-01-31)

US 6149911 A (2000-11-21);  US 6558673 B1 (2003-05-06);

Available from: 2012-01-30 Created: 2012-01-30 Last updated: 2015-01-28Bibliographically approved

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Nygren, Per-ÅkeUhlén, Mathias
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