ORGN 31-Secondary interaction in hydroxy-containing phosphinooxazolines
2007 (English)In: Abstract of Papers of the American Chemical Society, ISSN 0065-7727, Vol. 234, 31-ORGN- p.Article in journal (Other academic) Published
Phosphinooxazolines, first employed by Williams, Pfaltz, and Helmchen, serve as versatile ligands for a variety of asym. catalytic reactions. The hydroxy group in hydroxy-contg. phosphinooxazolines such as 1 can take part in hydrogen bonding to low valent metal ions, thereby affecting the conformation and, as a result, the stereochem. of catalytic reactions. The hydroxy group is also capable of coordinating to high valent metal ions via the oxygen atom, resulting in more rigid complexes. This leads for example to enhanced enantioselectivity in Rh- and Ir-catalyzed hydrosilylations of prochiral ketones. The influence of these secondary interaction on the conformation and dynamics of metal complexes and on the selectivity in catalytic reactions will be discussed.
Place, publisher, year, edition, pages
2007. Vol. 234, 31-ORGN- p.
IdentifiersURN: urn:nbn:se:kth:diva-71038ISI: 000207594300231OAI: oai:DiVA.org:kth-71038DiVA: diva2:486437
234th ACS National Meeting, Boston, MA
QC 201203062012-01-302012-01-302012-03-06Bibliographically approved