2009 (English)In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, E-ISSN 1091-6490, Vol. 106, no 51, 21842-21847 p.Article in journal (Refereed) Published
Filtered back-projection and weighted back-projection have long been the methods of choice within the electron microscopy com- munity for reconstructing the structure of macromolecular assem- blies from electron tomography data. Here, we describe electron lambda-tomography, a reconstruction method that enjoys the ben- efits of the above mentioned methods, namely speed and ease of implementation, but also addresses some of their shortcomings. In particular, compared to these standard methods, electron lambda- tomography is less sensitive to artifacts that come from structures outside the region that is being reconstructed, and it can sharpen boundaries.
Place, publisher, year, edition, pages
National Academy Press, 2009. Vol. 106, no 51, 21842-21847 p.
local tomography, limited angle tomography, microlocal analysis, electron tomography
Mathematical Analysis Structural Biology
Research subject SRA - E-Science (SeRC); SRA - Molecular Bioscience
IdentifiersURN: urn:nbn:se:kth:diva-71137DOI: 10.1073/pnas.0906391106ISI: 000272994200069ScopusID: 2-s2.0-76049103121OAI: oai:DiVA.org:kth-71137DiVA: diva2:486616
FunderSwedish e‐Science Research Center
QC 201201312012-01-302012-01-302012-01-31Bibliographically approved