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The role of material anisotropy in abdominal aortic aneurysm wall mechanics
Universita degli Studi di Roma Tor Vergata Via del Politecnico, Italy.
2008 (English)In: WCCM8: Proceedings of the 8th World Congress on Computational Mechanics, 2008Conference paper (Refereed)
Abstract [en]

The prevalence of AAA is growing along with population age and according to different studies AAA rupture is the 13th most common cause of death in the U.S., causing an estimated 15,000 deaths per year. In biomechanical terms, AAA rupture is a phenomenon that occurs when the developing mechanical stresses within the aneurysm inner wall, as a result of the exerted intraluminal pressure, exceed the failure strength of the aortic tissue. To obtain a reliable estimation of wall stress, it is necessary to perform an accurate three-dimensional reconstruction of the AAA geometry and model an appropriate constitutive law for the aneurysmal tissue material characterization. In this regard, a recent study on the biaxial mechanical behavior of human AAA tissue specimens [1] demonstrates that aneurysmal arterial tissue behaves mechanically anisotropic. The objectives of the present work are to determine the effect of material anisotropy of the aneurysmal abdominal aorta on wall stress distribution and to establish a comparison of wall mechanics between ruptured and unruptured aneurysms.

Place, publisher, year, edition, pages
Keyword [en]
Aneurysm, Wall Stress, Soft Tissue Mechanics, Computational Modeling
National Category
Biological Sciences
URN: urn:nbn:se:kth:diva-72279OAI: diva2:487400
8th World Congress on Computational Mechanics, 5th. European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008). Venice, Italy. June 30 – July 5
QC 20120201Available from: 2012-01-31 Created: 2012-01-31 Last updated: 2012-02-01Bibliographically approved

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Martufi, Giampaolo
Biological Sciences

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