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Chapter 61: Theoretical aspects on environmental monitoring in pharmaceutical cleanrooms
KTH, School of Architecture and the Built Environment (ABE), Civil and Architectural Engineering, Building Services Engineering (name changed to Building Service and Energy Systems 2012-03-01). Politecnico di Milano, Italy .
2006 (English)In: 37th R3-Nordic Contamination Control Symposium / [ed] Wirtanen, G; Salo, S, 2006, 441- p.Conference paper (Refereed)
Abstract [en]

Airborne particles are present throughout our environment. Particles vary greatly in their ability to affect not only visibility and climate, but also human health, quality of life and of industrial processes. Airborne particles are all examples of aerosols. Due to the large diversity of chemical, physical and microbiological properties existing among airborne particles, the way of performing measurements can not be the same for all the airborne particles present in the air environment. The measurement readings from a certain kind of airborne particle type may be different depending on the techniques and instruments used to perform the measurements. In the years, different methods and techniques were implemented and many instruments constructed in order to have the right equipment able to detect and to measure perfectly different kinds of airborne particles in their own environment without altering the real chemical, physical and microbiological characteristics. The theoretical aspects of environmental monitoring in pharmaceutical cleanrooms will be treated giving attention to the main measurement techniques used. Particle counters and microbiological air samplers are discussed taking into consideration the characteristics and the limitations they have under different working conditions. Results from experimental tests of different instruments are used for discussing the limitations of different instruments. Regulatory Requirements and Guidelines discussion help to find the specific field in which each measurement technique best fits the requirements.

Place, publisher, year, edition, pages
2006. 441- p.
, VTT SYMPOSIA, ISSN 0357-9387 ; 240
National Category
Engineering and Technology
URN: urn:nbn:se:kth:diva-75252ISI: 000243383100059ScopusID: 2-s2.0-42149162462ISBN: 951-38-6303-4OAI: diva2:490368
37th R3-Nordic Contamination Control Symposium. Tampere, FINLAND. MAY 29-31, 2006

QC 20120206

Available from: 2012-02-05 Created: 2012-02-05 Last updated: 2014-11-06Bibliographically approved

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Romano, Francesco
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