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[Vasopressin: the ontogeny of antidiuretic action at the cellular level].
KTH, School of Engineering Sciences (SCI), Applied Physics, Cell Physics.
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1989 (Russian)In: Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova, ISSN 0015-329X, Vol. 75, no 7, 970-9 p.Article in journal (Refereed) Published
Abstract [ru]

The data on the development of molecular mechanism of the antidiuretic effect of vasopressin and the molecular structure of the AVP receptor, cytosolic cAMP-dependent protein-kinases and renal response to AVP, are discussed. The experiments were performed in normal rats and mice, nephrogenic diabetes insipidus mutants and rats treated with cortisol in early postnatal period. The development of the kidney sensitivity to AVP seems to be closely connected with the development of the molecular structure of the AVP receptor, age-related increase of the AVP-activated adenylate cyclase, and the maturation of cAMP-dependent protein kinases.

Place, publisher, year, edition, pages
1989. Vol. 75, no 7, 970-9 p.
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Cell Biology
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URN: urn:nbn:se:kth:diva-80476PubMedID: 2530119OAI: oai:DiVA.org:kth-80476DiVA: diva2:496356
Note
NR 20140805Available from: 2012-02-09 Created: 2012-02-09 Last updated: 2012-02-09Bibliographically approved

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