[The functional characteristics of Gs-protein in the developing mammalian kidney].
1994 (Russian)In: Fiziologicheskiĭ zhurnal imeni I.M. Sechenova / Rossiĭskaia akademiia nauk, ISSN 1027-3646, Vol. 80, no 7, 81-7 p.Article in journal (Refereed) Published
Characteristics of G-proteins were studied in renal medulla of rats and mice of different ages. It was established that G-protein alpha-subunit gene expression has a specific dynamics with maximum on the 5-8-th day of life and at the end of weaning. It was shown that vasopressin does not stimulate G-protein GTPase activity in membrane preparations from immature kidneys. The differences of G-protein chromatographic characteristics were revealed. It is suggested that the development of vasopressin sensitivity of the kidney is related with the changes in G-protein system.
Place, publisher, year, edition, pages
1994. Vol. 80, no 7, 81-7 p.
IdentifiersURN: urn:nbn:se:kth:diva-80473PubMedID: 7531086OAI: oai:DiVA.org:kth-80473DiVA: diva2:496362
NR 201408052012-02-092012-02-092012-02-09Bibliographically approved