3D-correlation-averaging for membrane-protein-crystals
2008 (English)In: EMC 2008 14th European Microscopy Congress, 2008, 55-56 p.Conference paper (Refereed)
Few 2-dimensional protein crystals can be used to determine high-resolution structures, whereas most electron crystallography projects remain at a resolution around 10 Ångström. This might be partly due to lack of flatness of many two-dimensional crystals . We have investigated this problem and suggest single particle projection matching (3D-correlation averaging) of locally averaged unit cells to improve the quality of three-dimensional maps. Theoretical considerations and tests on simulated data demonstrate the feasibility of this refinement method .
Place, publisher, year, edition, pages
2008. 55-56 p.
IdentifiersURN: urn:nbn:se:kth:diva-83079DOI: 10.1007/978-3-540-85228-5_28OAI: oai:DiVA.org:kth-83079DiVA: diva2:498669
EMC 2008, 14th European Microscopy Congress. Aachen, Germany. 1–5 September 2008
QC 201205092012-02-122012-02-122012-05-09Bibliographically approved