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Prostate cancer biomarkers
KTH, School of Biotechnology (BIO), Proteomics (closed 20130101). KTH, Centres, Science for Life Laboratory, SciLifeLab.ORCID iD: 0000-0002-4657-8532
KTH, School of Biotechnology (BIO), Proteomics (closed 20130101). KTH, Centres, Science for Life Laboratory, SciLifeLab.ORCID iD: 0000-0001-8141-8449
KTH, School of Biotechnology (BIO), Proteomics (closed 20130101). KTH, Centres, Science for Life Laboratory, SciLifeLab.ORCID iD: 0000-0001-8993-048X
2010 (English)Patent (Other (popular science, discussion, etc.))
Abstract [en]

The present disclosure relates to a method of determining whether a mammalian subject belongs to a first or a second group of subjects, wherein the risk of having a prostate cancer, such as an aggressive prostate cancer, is higher in the first group than in the second group. The method comprises the steps of: a) evaluating an amount of unglycosylated CNDP1 protein in a sample derived from blood, semen or urine from the subject and determining a sample value corresponding to the evaluated amount; b) comparing the sample value with a predetermined reference value; and if the sample value is lower than or equal to the reference value, c1) concluding that the subject belongs to the first group; and if the sample value is higher than the reference value, c2) concluding that the subject belongs to the second group. Further, the present disclosure relates to a similar method based on the protein HCRTR1 as well as corresponding uses and means useful when carrying out the methods.

Place, publisher, year, edition, pages
2010.
National Category
Medical Biotechnology
Identifiers
URN: urn:nbn:se:kth:diva-84255OAI: oai:DiVA.org:kth-84255DiVA: diva2:499251
Patent
EP 2390665A1
Note

QS 2015

Available from: 2012-02-13 Created: 2012-02-13 Last updated: 2015-01-19Bibliographically approved

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Schwenk, JochenUhlén, Mathias

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