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Perfusion of an IgG producing CHO cell line at very high cell density by ATF or by TFF in WAVE Bioreactor™
KTH, School of Biotechnology (BIO), Bioprocess Technology. (Cell Technology Group)
KTH, School of Biotechnology (BIO), Bioprocess Technology. (Cell Technology Group)
KTH, School of Biotechnology (BIO), Bioprocess Technology. (Cell Technology Group)
KTH, School of Biotechnology (BIO), Bioprocess Technology. (Cell Technology Group)ORCID iD: 0000-0002-0841-8845
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2011 (English)Conference paper, Published paper (Other academic)
Abstract [en]

Perfusion of an IgG producing CHO cell line was performed in a WAVE Bioreactor™ using either Alternating Tangential Flow or Tangential Flow Filtration. The properties and performances obtained with both filtration systems were compared. Very high cell densities were achieved and could be stably maintained. Then the cell density could be significantly further increased showing the capacity of the system set-up.

Place, publisher, year, edition, pages
2011.
Keyword [en]
perfusion, hollow fiber filter, perfusion, ATF, TFF, CHO cells
National Category
Medical Biotechnology
Research subject
SRA - Molecular Bioscience
Identifiers
URN: urn:nbn:se:kth:diva-87428OAI: oai:DiVA.org:kth-87428DiVA: diva2:501643
Conference
Bioprocessing Summit, Boston, MA, USA, Aug. 22-25, 2011 - Optimizing Cell Culture Technology
Note
Invited speaker at the Bioprocessing Summit, Boston, MA, USA, Aug. 22-25, 2011 - Optimizing Cell Culture Technology. QC 20120319Available from: 2012-02-14 Created: 2012-02-14 Last updated: 2012-03-19Bibliographically approved

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http://www.bioprocessingsummit.com/uploadedFiles/Bioprocessing_Summit/11/2011_Bioprocessing_Summit_Brochure.pdf

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Zhang, YeChotteau, Veronique

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Clincke, Marie-FrancoiseMölleryd, CarinSamani, Puneeth KZhang, YeLindskog, EvaChotteau, Veronique
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CiteExportLink to record
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Citation style
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  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
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More styles
Language
  • de-DE
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  • en-US
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