Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Dendrimers with interior and exterior functionalities comprising of azide or alkyne groups for post- functionalization by huisgen click cycloaddition
KTH, School of Chemical Science and Engineering (CHE), Fibre and Polymer Technology, Coating Technology.ORCID iD: 0000-0002-9372-0829
KTH, School of Chemical Science and Engineering (CHE), Fibre and Polymer Technology, Coating Technology.ORCID iD: 0000-0002-9200-8004
KTH, School of Chemical Science and Engineering (CHE), Fibre and Polymer Technology, Coating Technology.
2008 (English)Patent (Other (popular science, discussion, etc.))
Abstract [en]

Novelty: A dendritic polymer comprising a core and repeating units, is new. Every repeating unit is bound to other unit(s) with bond(s) consisting of an ester, amide, thioether, ether, urethane, amine or imine.Use: The dendritic polymer is used for drug delivery systems, tissue engineering, data storage devices, markers for imaging, diagnostics, vaccines, phototherapeutics, optical devices, semiconductor, bioactive hydrogels and/or catalysts; for manufacture of a particle and a hydrogel (claimed); and for coatings, polyfunctional initiators for controlled radical polymerization or living free-radical polymerization techniques, ring-opening metathesis polymerization and ring-opening polymerization, dental and other composite materials, additives to control viscosity, rheology, solubility and stabilizing capacity, hybrid organic-inorganic materials, water-soluble materials, amphiphilic architectures, well-defined building blocks for precise architectural control, deposition of dendrimers on solid surfaces, dispersing agents for nanoparticles, dendrimer vehicles for encapsulation and/or delivery, and dendrimer scaffolds. The particle is used in encapsulation of low molecular compounds such as potent drugs, chelating species and fluorescent dyes.Advantage: The dendritic polymer can be functionalized both in the interior and in the exterior. It is possible to use a one-pot growth of dendritic polymer. There is provided the possibility to have more functional groups in a dendritic polymer compared to conventional polymer. When comparing the number of functional groups of a dendrimer based on A'B' x C' y -monomers with a traditional dendrimer based A'B' x -monomers, it is evident that the intrinsic functionality provides a larger number of available functional groups for post-modification. There is provided the possibility of a synthesis which is very robust, can be performed in various solvents, performed at both ambient and elevated temperatures, performed at atmospheric pressure as well as elevated, performed in a variety of gases including oxygen, nitrogen or argon. The synthesis has a high yield making the manufacture economical. There is the possibility to exclude an activation step prior to post-functionalization of a dendritic polymer. There is provided the possibility to add different types of functional groups simultaneously both to inner layer and/or to the outer layer.

Place, publisher, year, edition, pages
2008.
National Category
Polymer Chemistry Polymer Technologies
Identifiers
URN: urn:nbn:se:kth:diva-87766OAI: oai:DiVA.org:kth-87766DiVA: diva2:501851
Patent
WO2009136853A1
Note

QS 2014

Available from: 2012-02-14 Created: 2012-02-14 Last updated: 2015-01-12Bibliographically approved

Open Access in DiVA

No full text

Other links

Espacenet.com

Authority records BETA

Hult, AndersMalkoch, Michael

Search in DiVA

By author/editor
Hult, AndersMalkoch, MichaelAntoni, Per
By organisation
Coating Technology
Polymer ChemistryPolymer Technologies

Search outside of DiVA

GoogleGoogle Scholar

urn-nbn

Altmetric score

urn-nbn
Total: 50 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf