Tailoring magnetic microspheres with controlled porosity
2007 (English)In: Heterogeneous Integration of Materials for Passive Components and Smart Systems: MATERIALS RESEARCH SOCIETY SYMPOSIUM PROCEEDINGS / [ed] Nino, JC; Roozeboom, F; Muralt, P; TrolierMcKinstry, S; LaVan, D, Materials Research Society, 2007, Vol. 969, 93-98 p.Conference paper (Refereed)
The synthesis of organic and inorganic nano- and microspheres has attracted much interest for a variety of applications ranging from drug delivery to chemical storage and catalysis. We recently demonstrated the assembly of magnetic nanoparticles and polycations into hybrid microspheres in a single-step synthesis via complex coacervation. These microspheres showed viability for bio-applications as indicated by toxicity tests, and are therefore potential targeted drug delivery devices, as they can be directed magnetically. This work reports the recent progress on the potential use of these assemblies in drug release by controlling their porosity. Fluorescein tagged dextran molecules with different MW have been infiltrated into these entities to determine critical pore size by confocal fluorescence microscopy. Different physicochemical characterization results are also presented.
Place, publisher, year, edition, pages
Materials Research Society, 2007. Vol. 969, 93-98 p.
, Materials Research Society Symposium Proceedings, ISSN 0272-9172
PARTICLES; POLYMERIZATION; NANOPARTICLES; BIOSENSOR; THERAPY
IdentifiersURN: urn:nbn:se:kth:diva-86778ISI: 000248834600012ISBN: 978-1-55899-926-8OAI: oai:DiVA.org:kth-86778DiVA: diva2:502713
Symposium on Heterogeneous Integration of Materials for Passive Components and Smart Systems held at the 2006 MRS Fall Meeting, Boston, MA, NOV 27-29, 2006
cited By (since 1996) 0
QC 201202162012-02-162012-02-132012-02-16Bibliographically approved