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Derivatives of the B or Z domain from staphylococcal protein A (SPA) interacting with at least one domain of human factor VIII
KTH, School of Biotechnology (BIO), Proteomics.ORCID iD: 0000-0001-8993-048X
1999 (English)Patent (Other (popular science, discussion, etc.))
Abstract [en]

The present invention relates to modified polypeptides which are derivatives of the B domain or Z domain from staphylococcal protein A (SPA), wherein between 1 and 20 amino acid residues of the said B or Z domain have been substituted by other amino acid residues, said substitution being made without substantial loss of the basic structure and stability of the said B or Z domain, and said substitution resulting in interaction capacity of the said polypeptide with at least one domain of human Factor VIII protein.

Place, publisher, year, edition, pages
1999.
National Category
Engineering and Technology
Identifiers
URN: urn:nbn:se:kth:diva-91203OAI: oai:DiVA.org:kth-91203DiVA: diva2:508808
Patent
EP 1179014 (2008-12-10)
Note

JP 4578690-B2 (2010-11-10)

Available from: 2012-03-09 Created: 2012-03-09 Last updated: 2013-08-06Bibliographically approved

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Uhlén, Mathias

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