Derivatives of the B or Z domain from staphylococcal protein A (SPA) interacting with at least one domain of human factor VIII
1999 (English)Patent (Other (popular science, discussion, etc.))
The present invention relates to modified polypeptides which are derivatives of the B domain or Z domain from staphylococcal protein A (SPA), wherein between 1 and 20 amino acid residues of the said B or Z domain have been substituted by other amino acid residues, said substitution being made without substantial loss of the basic structure and stability of the said B or Z domain, and said substitution resulting in interaction capacity of the said polypeptide with at least one domain of human Factor VIII protein.
Place, publisher, year, edition, pages
Engineering and Technology
IdentifiersURN: urn:nbn:se:kth:diva-91203OAI: oai:DiVA.org:kth-91203DiVA: diva2:508808
EP 1179014 (2008-12-10)
JP 4578690-B2 (2010-11-10)2012-03-092012-03-092013-08-06Bibliographically approved