Surface Assisted Laser Desorption Ionization-Mass Spectrometry (SALDI-MS) for Analysis of Polyester Degradation Products
2012 (English)In: Journal of the American Society for Mass Spectrometry, ISSN 1044-0305, E-ISSN 1879-1123, Vol. 23, no 6, 1071-1076 p.Article in journal (Refereed) Published
Novel surface assisted laser desorption ionization-mass spectrometry (SALDI-MS) method was developed for rapid analysis of low molecular mass polyesters and their degradation products by laser desorption ionization-mass spectrometry. Three polycaprolactone materials were analyzed by the developed method before and after hydrolytic degradation. The signal-to-noise values obtained by SALDI-MS were 20-100 times higher compared with the ones obtained by using traditional MALDI-MS matrices. A clean background at low mass range and higher resolution was obtained by SALDI-MS. Different nanoparticle, cationizing agent, and solvent combinations were evaluated. Halloysite nanoclay and magnesium hydroxide showed the best potential as SALDI surfaces. The SALDI-MS spectrum of the polyester hydrolysis products was verified by ESI-MS. The developed SALDI-MS method possesses several advantages over existing methods for similar analyses.
Place, publisher, year, edition, pages
2012. Vol. 23, no 6, 1071-1076 p.
surface assisted laser desorption ionization-mass spectrometry (SALDI-MS), polyester, polycaprolactone, degradation, nanoparticles
Polymer Technologies Polymer Chemistry Analytical Chemistry
IdentifiersURN: urn:nbn:se:kth:diva-91483DOI: 10.1007/s13361-012-0360-8ISI: 000303685800010ScopusID: 2-s2.0-84864866736OAI: oai:DiVA.org:kth-91483DiVA: diva2:510420
Updated from submitted to published. QC 201206072012-03-162012-03-162014-10-02Bibliographically approved