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XRF för kvalitetskontroll av farmaceutiska råvaror: - metodutveckling och utbildning av användare
KTH, School of Engineering Sciences (SCI).
2012 (Swedish)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Abstract [sv]

Detta examensarbete dokumenterar arbetet med utveckling, införande och dokumentation av en nymetod för identitetsbestämning av farmaceutiska råvaror med röntgenfluorescens. Metoden ärutvecklad för att användas på laboratorier för kvalitetskontroll på AstraZeneca i Södertälje. Syftetmed arbetet var att utveckla en robust och effektiv metod samt att utbilda användarna i dethanteringssätt som krävs för att utföra snabba och korrekta analyser. Rapporten presenterarteknologin bakom röntgenfluorescensinstrument och vilka felkällor som kan påverka resultaten samtde pedagogiska teorier som använts för att beskriva det praktiska arbete som äger rum pålaboratoriet. Metoden och de försök som föregick metoden presenteras, och resultat och beslutdiskuteras. Hur utbildningen planerades, genomfördes och utvärderades presenteras också.

Abstract [en]

This master thesis is the documented work of the development, implementation and documentationof a new method for identification of pharmaceuticals excipients using X-ray fluorescence. Themethod is supposed to be used at the laboratory for quality control at AstraZeneca, Södertälje. Thepurpose of the thesis was to develop a stout and effective method and to educate the users in theskills needed to perform fast and correct analyses. This thesis presents the technology behind XRFinstruments and which sources of errors that could affect the results as well as the pedagogicaltheories used to describe the practical work that takes place at the laboratory. The method and theexperiment that preceded the method are presented, and the results and decisions are discussed.How the education was planned, performed and evaluated is also presented.

Place, publisher, year, edition, pages
2012.
Keyword [en]
X-ray fluorescence, pharmaceutical excipients, identification, development of methods, education of users, practical knowledge, routine and attention.
Keyword [sv]
Röntgenfluorescens, farmaceutiska råvaror, identitetsbestämning, metodutveckling
National Category
Learning
Identifiers
URN: urn:nbn:se:kth:diva-93444OAI: oai:DiVA.org:kth-93444DiVA: diva2:516089
External cooperation
Astra Zeneca
Subject / course
Technology and Learning
Educational program
Master of Science in Engineering - Engineering and of Education
Uppsok
Technology
Supervisors
Examiners
Available from: 2012-04-17 Created: 2012-04-17 Last updated: 2013-03-19Bibliographically approved

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CiteExportLink to record
Permanent link

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Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
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More styles
Language
  • de-DE
  • en-GB
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  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
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