Change search
ReferencesLink to record
Permanent link

Direct link
Antithrombotic properties of sulfated wood-derived galactoglucomannans
Show others and affiliations
2012 (English)In: Holzforschung, ISSN 0018-3830, Vol. 66, no 2, 149-154 p.Article in journal (Refereed) Published
Abstract [en]

Galactoglucomannans (GGMs) are water-soluble polysaccharides released and accumulated in process waters in the production of thermomechanical pulp. The general trend in the forestry industry is moving towards bio-refineries, for example utilizing these hemicelluloses as bioactive substances. At present, there is no industrial use of wood-derived mannans. In this study, GGMs extracted from thermomechanical pulp, as well as further carboxymethyl-ated galactoglucomannans (CM-GGMs), were sulfated to increase their antithrombotic properties. The products were characterized with Fourier transform infrared spectroscopy, nuclear magnetic resonance and capillary electrophoresis. The carbohydrate composition and sulfur amounts were determined. The products' total charges were determined by polyelectrolyte titrations and their antithrombotic effect was measured based on the activated partial thromboplastin time. The results showed a significant increase in the antithrombotic effect of the sulfated galactoglucomannans from spruce wood and thus a potential new use for wood-derived mannans.

Place, publisher, year, edition, pages
2012. Vol. 66, no 2, 149-154 p.
Keyword [en]
activated partial thromboplastin time, anticoagulant, antithrombocity, carboxymethylation, galactoglucomannan, spruce wood, sulfated polysaccharide, Sulfated polysaccharides, Capillary electrophoresis, Carbohydrates, Fourier transform infrared spectroscopy, Industrial applications, Sulfur, Thermomechanical pulp, Wood, Capillaries, Coagulants, Electrophoresis, Fourier Analysis, Galactoglucomannans, Infrared Spectroscopy, Picea, Polysaccharides, Sulfates, Thermomechanical Pulps
National Category
Paper, Pulp and Fiber Technology
URN: urn:nbn:se:kth:diva-97873DOI: 10.1515/HF.2011.136ISI: 000300740500002ScopusID: 2-s2.0-84860630898OAI: diva2:534542
QC 20120618Available from: 2012-06-18 Created: 2012-06-15 Last updated: 2012-06-18Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textScopus

Search in DiVA

By author/editor
Xu, Chunlin
By organisation
In the same journal
Paper, Pulp and Fiber Technology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 46 hits
ReferencesLink to record
Permanent link

Direct link