Change search
ReferencesLink to record
Permanent link

Direct link
Photon-Counting Spectral Phase-Contrast Mammography
KTH, School of Engineering Sciences (SCI), Physics, Medical Imaging.
Show others and affiliations
2012 (English)In: Medical Imaging 2012: Physics Of Medical Imaging / [ed] Pelc, NJ; Nishikawa, RM; Whiting, BR, SPIE - International Society for Optical Engineering, 2012, 83130F- p.Conference paper (Refereed)
Abstract [en]

Phase-contrast imaging is an emerging technology that may increase the signal-difference-to-noise ratio in medical imaging. One of the most promising phase-contrast techniques is Talbot interferometry, which, combined with energy-sensitive photon-counting detectors, enables spectral differential phase-contrast mammography. We have evaluated a realistic system based on this technique by cascaded-systems analysis and with a task-dependent ideal-observer detectability index as a figure-of-merit. Beam-propagation simulations were used for validation and illustration of the analytical framework. Differential phase contrast improved detectability compared to absorption contrast, in particular for fine tumor structures. This result was supported by images of human mastectomy samples that were acquired with a conventional detector. The optimal incident energy was higher in differential phase contrast than in absorption contrast when disregarding the setup design energy. Further, optimal weighting of the transmitted spectrum was found to have a weaker energy dependence than for absorption contrast. Taking the design energy into account yielded a superimposed maximum on both detectability as a function of incident energy, and on optimal weighting. Spectral material decomposition was not facilitated by phase contrast, but phase information may be used instead of spectral information.

Place, publisher, year, edition, pages
SPIE - International Society for Optical Engineering, 2012. 83130F- p.
, Proceedings of SPIE, ISSN 0277-786X ; 8313
Keyword [en]
mammography, phase contrast, spectral imaging, detectability index, Talbot interferometry, photon counting
National Category
Medical and Health Sciences
URN: urn:nbn:se:kth:diva-99499DOI: 10.1117/12.910615ISI: 000304768000013ScopusID: 2-s2.0-84860387803ISBN: 978-0-8194-8962-3OAI: diva2:542361
Conference on Medical Imaging - Physics of Medical Imaging, FEB 05-08, 2012, San Diego, CA
QC 20120731Available from: 2012-07-31 Created: 2012-07-31 Last updated: 2012-07-31Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textScopus

Search in DiVA

By author/editor
Fredenberg, ErikDanielsson, Mats
By organisation
Medical Imaging
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 49 hits
ReferencesLink to record
Permanent link

Direct link