Structural and Hemodynamical analysis of Aortic Aneurysms from Computerized Tomography Angiography data
2010 (English)In: WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING, VOL 25, PT 4: IMAGE PROCESSING, BIOSIGNAL PROCESSING, MODELLING AND SIMULATION, BIOMECHANICS, 2010, 1584-1587 p.Conference paper (Refereed)
Evaluating rupture risk of Abdominal Aortic Aneurysms is critically important in reducing related mortality without unnecessarily increasing the rate of elective repair. According to the current clinical practice aneurysm rupture risk is (mainly) estimated from its maximum diameter and/or expansion rate; an approach motivated from statistics but known to fail often in individuals. In particular, the role of the Intraluminal Thrombus is unclear and further research is required to investigate and understand its multiple impacts on aneurysm disease. Biomechanical simulations might be helpful to explore this question, however, model development is time consuming and operator-variability limits their reliability. In this study we propose an automatic procedure to develop hemodynamic and structural models of healthy and diseased abdominal aortas, where Deformable Models segment Computerized Tomography Angiography data. In total 29 numerical models of the health and diseased abdominal aorta have been developed to investigate aneurysm's rupture risk and hemodynamic consequences of aneurismal dilations. The derived results underline the suitability of biomechanical simulations to enrich diagnostic information and to uncover mechanisms of aneurysm pathology.
Place, publisher, year, edition, pages
2010. 1584-1587 p.
, IFMBE Proceedings, ISSN 1680-0737 ; 25
Biomedical Laboratory Science/Technology
IdentifiersURN: urn:nbn:se:kth:diva-101612DOI: 10.1007/978-3-642-03882-2-420ISI: 000300975300420ScopusID: 2-s2.0-77950184550ISBN: 978-3-642-03881-5OAI: oai:DiVA.org:kth-101612DiVA: diva2:549701
World Congress on Medical Physics and Biomedical Engineering, SEP 07-12, 2009, Munich, GERMANY
QC 201209042012-09-052012-08-302012-09-05Bibliographically approved