Rational engineering of Candida antarctica lipase B for selective monoacylation of diols
2012 (English)In: Chemical Communications, ISSN 1359-7345, E-ISSN 1364-548X, Vol. 48, no 80, 10013-10015 p.Article in journal (Refereed) Published
The enzyme Candida antarctica lipase B was subjected to site directed mutagenesis suggested by molecular modelling. The selectivity for the enzyme increased towards a range of diols over their corresponding monoesters as an effect of the mutations.
Place, publisher, year, edition, pages
2012. Vol. 48, no 80, 10013-10015 p.
bacterial protein, lipase B, nucleophile
Biochemistry and Molecular Biology
IdentifiersURN: urn:nbn:se:kth:diva-103518DOI: 10.1039/c2cc34684bISI: 000308653800018ScopusID: 2-s2.0-84866397954OAI: oai:DiVA.org:kth-103518DiVA: diva2:561056
QC 201210172012-10-172012-10-152012-11-06Bibliographically approved