Metal release from stainless steel powders and massive sheets - comparison and implication for risk assessment of alloys
2013 (English)In: Environmental Sciences: Processes and Impacts, ISSN 2050-7887, Vol. 15, no 2, 381-392 p.Article in journal (Refereed) Published
Industries that place metal and alloy products on the market are required to demonstrate them being safe for all intended uses, and that any risks to humans, animals or the environment are adequately controlled. This requires reliable and robust in-vitro test procedures. The aim of this study is to compare the release of alloy constituents from stainless steel powders of different grades (focus on AISI 316L) and production routes into synthetic body fluids with the release of the same metals from massive sheet in relation to material and surface characteristics. The comparison is justified by the fact that the difference between massive surfaces and powders from a metal release/dissolution and surface perspective is not clearly elucidated within current legislations. Powders and abraded and aged (24 h) massive sheets were exposed to synthetic solutions of relevance for biological settings and human exposure routes, for periods up to one week. Concentrations of released iron, chromium, nickel, and manganese in solution were measured, and the effect of solution pH, acidity, complexation capacity, and proteins elucidated in relation to surface oxide composition and its properties. Implications for risk assessments based on in-vitro metal release data from alloys are elucidated.
Place, publisher, year, edition, pages
2013. Vol. 15, no 2, 381-392 p.
Patch Test Reactivity, Particles In-Vitro, Ion Release, Nickel Release, Pure Metals, Orthodontic Appliances, Ferrochromium Alloy, Contact-Dermatitis, Oxygen Reduction, Aisi 316l
IdentifiersURN: urn:nbn:se:kth:diva-105520DOI: 10.1039/C2EM30818EISI: 000315397700008ScopusID: 2-s2.0-84874439615OAI: oai:DiVA.org:kth-105520DiVA: diva2:571305
QC 201302132012-11-222012-11-222016-08-30Bibliographically approved