Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Asymmetric Transfer Hydrogenation Coupled with Dynamic Kinetic Resolution in Water: Synthesis of anti-beta-Hydroxy-alpha-amino Acid Derivatives
KTH, School of Chemical Science and Engineering (CHE), Chemistry, Organic Chemistry.
KTH, School of Chemical Science and Engineering (CHE), Chemistry, Organic Chemistry.
2012 (English)In: Organic Letters, ISSN 1523-7060, E-ISSN 1523-7052, Vol. 14, no 24, 6334-6337 p.Article in journal (Refereed) Published
Abstract [en]

The use of asymmetric transfer hydrogenation combined with dynamic kinetic resolution for the synthesis of beta-hydroxy-alpha-(tert-butoxycarbonyl)-amino esters in water is described. This procedure provides the desired amino alcohols in good yields, diastereoselectivities, and enantioselectivities. A surfactant is employed to achieve good yields due to the hydrophobic nature of both the catalyst and substrate. The reaction setup is operationally simple, and nondegassed water can be used as the solvent.

Place, publisher, year, edition, pages
2012. Vol. 14, no 24, 6334-6337 p.
Keyword [en]
Highly Enantioselective Synthesis, D-Erythro-Sphingosine, Organic-Synthesis, Aromatic Ketones, Aqueous-Media, Esters, Reduction, Catalyst, Depsipeptides, Complexes
National Category
Organic Chemistry
Identifiers
URN: urn:nbn:se:kth:diva-116423DOI: 10.1021/ol303115vISI: 000312564500055Scopus ID: 2-s2.0-84871570629OAI: oai:DiVA.org:kth-116423DiVA: diva2:589931
Note

QC 20130121

Available from: 2013-01-21 Created: 2013-01-18 Last updated: 2017-12-06Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textScopus

Search in DiVA

By author/editor
Seashore-Ludlow, BrintonSaint-Dizier, Francois
By organisation
Organic Chemistry
In the same journal
Organic Letters
Organic Chemistry

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 31 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf