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Regioselective synthesis of isoxazole-mercaptobenzimidazole hybrids and their in vivo analgesic and anti-inflammatory activity studies
KTH, School of Chemical Science and Engineering (CHE), Chemistry.
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2013 (English)In: Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, E-ISSN 1090-2120, Vol. 23, no 5, 1306-1309 p.Article in journal (Refereed) Published
Abstract [en]

Regioselective synthesis of isoxazole-mercaptobenzimidazole hybrids and their efficiency in in vivo analgesic and anti-inflammatory activity was described. A comparison of structure-activity relationship for there compounds was also emphasized.

Place, publisher, year, edition, pages
2013. Vol. 23, no 5, 1306-1309 p.
Keyword [en]
Isoxazole-benzimidazole hybrids, 1, 3-Dipolar cycloaddition, N-Heterocyclic carbene, Analgesic activity, Anti-inflammatory activity
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URN: urn:nbn:se:kth:diva-119447DOI: 10.1016/j.bmcl.2012.12.101ISI: 000314693400030Scopus ID: 2-s2.0-84873720775OAI: oai:DiVA.org:kth-119447DiVA: diva2:611299
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QC 20130315

Available from: 2013-03-15 Created: 2013-03-14 Last updated: 2017-12-06Bibliographically approved

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