Lipase-Catalyzed Dynamic Kinetic Asymmetric Transformation to Oxathiazinanones
(English)Article in journal (Other academic) Submitted
A domino addition-lactonization pathway has been applied to a dynamic covalent resolution protocol, leading to efficient oxathiazinanone formation as well as chiral discrimination. A new, double biocatalytic pathway has furthermore been proposed and evaluated where initial product inhibition could be efficiently circumvented.
IdentifiersURN: urn:nbn:se:kth:diva-123685OAI: oai:DiVA.org:kth-123685DiVA: diva2:628532
QS 20132013-06-142013-06-142013-06-14Bibliographically approved