Rapid Fabrication Of OSTE+ Microfluidic Devices With Lithographically Defined Hydrophobic/ Hydrophilic Patterns And Biocompatible Chip Sealing
2013 (English)In: 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013, Freiburg, Germany: NO , 2013, 134-136 p.Conference paper (Refereed)
Here we present an uncomplicated and robust method for rapid prototyping of microfluidic devices featuring: 1) lithographically defined, permanently surface modified hydrophilic and hydrophobic regions with contact angles varying from 18o to 118o, in which all four channel walls are surface modified in a single step using polymer chain grafting; 2) polymer chains grafted from open surfaces before bonding, making this method suitable for batch fabrication; 3) biomolecule-compatible, room temperature, dry, homogeneous chip-sealing, in which native as well as hydrophobic/hydrophilic modified OSTE+ surfaces allow for epoxy-epoxy and thiol-epoxy covalent bonding, hence greatly simplifying alignment and dramatically increasing device yields. We demonstrate the method with a functional microfluidic device. This represents a complete, simplified and robust method for batch-manufacturing compatible prototyping of microfluidic devices with tunable mechanical and surface properties.
Place, publisher, year, edition, pages
Freiburg, Germany: NO , 2013. 134-136 p.
Theracage, OSTE+, surface modification, lithography
Engineering and Technology
IdentifiersURN: urn:nbn:se:kth:diva-124640ScopusID: 2-s2.0-84905743758ISBN: 978-0-9798064-6-9OAI: oai:DiVA.org:kth-124640DiVA: diva2:637920
The 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 27-31 October 2013, Freiburg, Germany