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A general strategy for obtaining biodegradable polymer shelled microbubbles as theranostic devices
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2013 (English)In: Chemical Communications, ISSN 1359-7345, E-ISSN 1364-548X, Vol. 49, no 51, 5763-5765 p.Article in journal (Refereed) Published
Abstract [en]

Fabrication of multifunctional ultrasound contrast agents (UCAs) has been recently addressed by several research groups. A versatile strategy for the synthesis of UCA precursors in the form of biodegradable vesicles with a biocompatible crosslinked polymer shell is described. Upon ultrasound irradiation, acoustic droplet vaporization transforms such particles into microbubbles behaving as UCAs. This proof of concept entails the features of a potential theranostic microdevice.

Place, publisher, year, edition, pages
2013. Vol. 49, no 51, 5763-5765 p.
Keyword [en]
Ultrasound, microbubbles, theranostic, ADV, acoustic droplet vaporization
National Category
Medical Materials Other Medical Engineering Medical Laboratory and Measurements Technologies Other Physics Topics
Research subject
SRA - Molecular Bioscience
URN: urn:nbn:se:kth:diva-124647DOI: 10.1039/C3CC42037JISI: 000319777500016ScopusID: 2-s2.0-84878636038OAI: diva2:637954

QC 20131211

Available from: 2013-07-24 Created: 2013-07-24 Last updated: 2013-12-11Bibliographically approved

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Grishenkov, Dmitry
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Medical Imaging
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