A polymer neural probe with tunable flexibility
2013 (English)In: 2013 6th International IEEE/EMBS Conference on Neural Engineering (NER), 2013, 691-694 p.Conference paper (Refereed)
A novel polymeric material, off stoichiometry thiol-ene-epoxy (OSTE+), has been evaluated for the fabrication of neural implants. OSTE+ is easily photo-structurable and exhibits mechanical properties suitable for stable implantation of the probe into brain tissue, while being sufficiently soft at physiological temperatures to reduce living tissue damage. The facile processing of OSTE+ allows use in applications where SU-8 or polyimide currently are the materials of choice. Uniquely, OSTE+ has a Young’s modulus of 1.9 GPa at 10 °C decreasing almost two orders of magnitude to 30 MPa at 40 °C, which can be compared to the Young’s modulus of 2.1 GPa for SU-8. We show a probe, with nine gold electrode sites, implanted into 0.5% agar at 40 °C using active cooling during the implantation.
Place, publisher, year, edition, pages
2013. 691-694 p.
, International IEEE/EMBS Conference on Neural Engineering, ISSN 1948-3546
Implantable neural probes, Biocompatibility, Thiol-ene-epoxy, OSTE+
Medical Engineering Materials Engineering Electrical Engineering, Electronic Engineering, Information Engineering
IdentifiersURN: urn:nbn:se:kth:diva-125010DOI: 10.1109/NER.2013.6696028ScopusID: 2-s2.0-84897675358ISBN: 978-1-4673-1969-0OAI: oai:DiVA.org:kth-125010DiVA: diva2:638764
2013 6th International IEEE/EMBS Conference on Neural Engineering (NER); San Diego, CA, USA, 6-8 November 2013
QC 201402142013-08-022013-08-022014-02-14Bibliographically approved