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Effect of Prestimulus Alpha Power, Phase, and Synchronization on Stimulus Detection Rates in a Biophysical Attractor Network Model
KTH, School of Computer Science and Communication (CSC), Computational Biology, CB.
KTH, School of Computer Science and Communication (CSC), Computational Biology, CB.ORCID iD: 0000-0001-6553-823X
KTH, School of Computer Science and Communication (CSC), Computational Biology, CB.ORCID iD: 0000-0002-2358-7815
2013 (English)In: Journal of Neuroscience, ISSN 0270-6474, E-ISSN 1529-2401, Vol. 33, no 29, 11817-11824 p.Article in journal (Refereed) Published
Abstract [en]

Spontaneous oscillations measured by local field potentials, electroencephalograms and magnetoencephalograms exhibit a pronounced peak in the alpha band (8-12 Hz) in humans and primates. Both instantaneous power and phase of these ongoing oscillations have commonly been observed to correlate with psychophysical performance in stimulus detection tasks. We use a novel model-based approach to study the effect of prestimulus oscillations on detection rate. A previously developed biophysically detailed attractor network exhibits spontaneous oscillations in the alpha range before a stimulus is presented and transiently switches to gamma-like oscillations on successful detection. We demonstrate that both phase and power of the ongoing alpha oscillations modulate the probability of such state transitions. The power can either positively or negatively correlate with the detection rate, in agreement with experimental findings, depending on the underlying neural mechanism modulating the oscillatory power. Furthermore, the spatially distributed alpha oscillators of the network can be synchronized by global nonspecific weak excitatory signals. These synchronization events lead to transient increases in alpha-band power and render the network sensitive to the exact timing of target stimuli, making the alpha cycle function as a temporal mask in line with recent experimental observations. Our results are relevant to several studies that attribute a modulatory role to prestimulus alpha dynamics.

Place, publisher, year, edition, pages
2013. Vol. 33, no 29, 11817-11824 p.
Keyword [en]
Cortical Representations, Attentional Modulation, Neuronal Mechanisms, Visual-Attention, Auditory-Cortex, Mu Rhythm, Oscillations, Inhibition, Dynamics, Neocortex
National Category
Neurosciences
Identifiers
URN: urn:nbn:se:kth:diva-126886DOI: 10.1523/JNEUROSCI.5155-12.2013ISI: 000321893500010Scopus ID: 2-s2.0-84880438564OAI: oai:DiVA.org:kth-126886DiVA: diva2:642845
Funder
Swedish Research Council, VR-621-2009-3807VinnovaSwedish Foundation for Strategic Research EU, FP7, Seventh Framework Programme, EU-FP7-FET-269921
Note

QC 20130823

Available from: 2013-08-23 Created: 2013-08-22 Last updated: 2017-12-06Bibliographically approved

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Herman, Pawel

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