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Consequences of the dynamic triple peak impact factor in traumatic brain injury as measured with numerical simulation
KTH, School of Technology and Health (STH), Medical Engineering, Neuronic Engineering. Section of Neurosurgery, Division of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
KTH, School of Technology and Health (STH), Medical Engineering, Neuronic Engineering.
2013 (English)In: Frontiers in Neurology, ISSN 1664-2295, Vol. 4 MARArticle in journal (Refereed) Published
Abstract [en]

There is a lack of knowledge about the direct neuromechanical consequences in traumatic brain injury (TBI) at the scene of accident. In this study we use a finite element model of the human head to study the dynamic response of the brain during the first milliseconds after the impact with velocities of 10, 6, and 2 meters/second (m/s), respectively. The numerical simulation was focused on the external kinetic energy transfer, intracranial pressure (ICP), strain energy density and first principal strain level, and their respective impacts to the brain tissue. We show that the oblique impacts of 10 and 6 m/s resulted in substantial high peaks for the ICP, strain energy density, and first principal strain levels, however, with different patterns and time frames. Also, the 2 m/s impact showed almost no increase in the above mentioned investigated parameters. More importantly, we show that there clearly exists a dynamic triple peak impact factor to the brain tissue immediately after the impact regardless of injury severity associated with different impact velocities. The dynamic triple peak impacts occurred in a sequential manner first showing strain energy density and ICP and then followed by first principal strain. This should open up a new dimension to better understand the complex mechanisms underlying TBI. Thus, it is suggested that the combination of the dynamic triple peak impacts to the brain tissue may interfere with the cerebral metabolism relative to the impact severity thereby having the potential to differentiate between severe and moderate TBI from mild TBI.

Place, publisher, year, edition, pages
2013. Vol. 4 MAR
Keyword [en]
Dynamic triple peak impact, Finite element modeling, Intracranial pressure, Kinetic energy transfer, Strain energy density and first principal strain, Traumatic brain injury
National Category
URN: urn:nbn:se:kth:diva-134249DOI: 10.3389/fneur.2013.00023ScopusID: 2-s2.0-84878779466OAI: diva2:665889

QC 20131121

Available from: 2013-11-21 Created: 2013-11-20 Last updated: 2013-11-21Bibliographically approved

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