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Network Inference With Hidden Units
KTH, Centres, Nordic Institute for Theoretical Physics NORDITA.
2014 (English)In: Mathematical Biosciences and Engineering, ISSN 1547-1063, E-ISSN 1551-0018, Vol. 11, no 1, 149-165 p.Article in journal (Refereed) Published
Abstract [en]

We derive learning rules for finding the connections between units in stochastic dynamical networks from the recorded history of a "visible" subset of the units. We consider two models. In both of them, the visible units are binary and stochastic. In one model the "hidden" units are continuous-valued, with sigmoidal activation functions, and in the other they are binary and stochastic like the visible ones. We derive exact learning rules for both cases. For the stochastic case, performing the exact calculation requires, in general, repeated summations over an number of configurations that grows exponentially with the size of the system and the data length, which is not feasible for large systems. We derive a mean field theory, based on a factorized ansatz for the distribution of hidden-unit states, which offers an attractive alternative for large systems. We present the results of some numerical calculations that illustrate key features of the two models and, for the stochastic case, the exact and approximate calculations.

Place, publisher, year, edition, pages
2014. Vol. 11, no 1, 149-165 p.
Keyword [en]
Network inference, latent variables, kinetic Ising models, mean field theory, hidden units
National Category
Bioinformatics (Computational Biology)
Identifiers
URN: urn:nbn:se:kth:diva-137450DOI: 10.3934/mbe.2014.11.149ISI: 000326979900011OAI: oai:DiVA.org:kth-137450DiVA: diva2:679893
Conference
10th International Workshop on Neural Coding (NC), SEP 02-07, 2012, Prague, Czech Republic
Note

QC 20131217

Available from: 2013-12-17 Created: 2013-12-13 Last updated: 2017-12-06Bibliographically approved

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