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Relationships Between Skin Properties and Body Water Level
KTH, School of Technology and Health (STH), Medical Engineering.
KTH, School of Technology and Health (STH), Medical Engineering.
2013 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesisAlternative title
Förhållanden mellan hudegenskaper och kroppens vattennivå (Swedish)
Abstract [en]

A need for a quantitative method to determine body water level has been identified by a team of Clinical Innovation Fellows at the Centre for Technology in Medicine and Health (CTMH). A reliable way to determine body water level would bring great benefits to the healthcare sector, where no optimal method is available at the time of writing. A possible solution is a sensor that would measure alterations in skin properties due to changes in total body water. CTMH has had an idea of such a sensor, which is evaluated in this work. At an early stage of this evaluation process, it became clear that the research regarding correlations between skin properties and body hydration level was not sufficient to warrant the initiation of a sensor development process. Therefore, the main objective of this thesis became to investigate such correlations.

An extensive literature review is presented, from which an experiment was developed. The experiment was performed on four human test subjects and involved measurements of skin thickness and elasticity parameters, before and after a weight loss of 3.2-3.7 % due to dehydration. The results showed clear decreases in skin thickness and indications of alterations in skin distensibility as well as in the skin’s immediate elastic response to applied negative pressure. It could also be seen that skin at different body sites does not respond in the same way - calves showed more distinct results than thighs and volar forearm.

The material provided in this thesis encourages further studies of the correlation between the mentioned properties and total body water. If a predictable correlation can be found, a sensor development process could start. A reliable way to determine body water level would bring great benefits to the healthcare sector, where no optimal method is available at the time of writing.

Abstract [sv]

Ett behov av att kvantitativt kunna mäta kroppens vattennivå har identifierats av Clinical Innovation Fellowship vid Centrum för Teknik i Medicin och Hälsa (CTMH). Ett tillförlitligt sätt att mäta kroppens vattennivå skulle gynna hälso- och sjukvården på många sätt då ingen optimal metod är tillgänglig i dagsläget.

En möjlig lösning skulle kunna vara en sensor som mäter variationer i hudegenskaper till följd av förändringar i kroppens vattennivå. CTMH har haft en idé om en sådan sensor, vilken utvärderas i detta arbete. I ett tidigt skede av utvärderingsprocessen framkom det tydligt att tillräcklig forskning saknades gällande korrelationer mellan hudens egenskaper och kroppens vattennivå. Det huvudsakliga syftet med detta masterexamensarbete blev därför att undersöka sådana korrelationer.

En omfattande litteraturgransking gjordes, och utifrån denna utformades ett experiment. Experimentet utfördes på fyra testpersoner och innefattade mätningar av hudens tjocklek samt elasticitetsparameterar. Dessa utfördes före och efter viktnedgång av 3,2-3,7 % till följd av vattenförlust. Resultaten visade på en tydlig minskning av hudtjockleken samt indikationer på förändringar av hudens tänjbarhet samt dess omedelbara elastiska respons vid pålagt negativt tryck. Det visade sig också att huden inte reagerar på samma sätt på olika kroppsdelar - vader visade tydligare förändringar jämfört med lår och armar.

Det material som presenteras i detta examensarbete uppmuntrar till fortsatt utredning av korrelationer mellan de nämnda hudegenskaperna och kroppens vattennivå. Om det går att förutse korrelationer finns det förutsättningar för att påbörja utveckling av en sensor.

Place, publisher, year, edition, pages
2013. , 116 p.
Series
TRITA-STH, 2013:120
Keyword [en]
22 MHz, body water level, correlations, Cutometer, dehydration, distensibility, elasticity, humans, immediate elastic deformation, mechanical properties, skin, thickness, ultrasound, viscoelasticity
Keyword [sv]
22 MHz, Cutometer, dehydrering, direkt elastisk deformation, elasticitet, hud, korrelationer, kroppens vattennivå, mekaniska egenskaper, människor, tjocklek, töjbarhet, ultraljud, viskoelasticitet
National Category
Medical Engineering
Identifiers
URN: urn:nbn:se:kth:diva-133438OAI: oai:DiVA.org:kth-133438DiVA: diva2:683766
External cooperation
Center for Technology in Medicine and Health
Subject / course
Medical Engineering
Educational program
Master of Science in Engineering - Medical Engineering
Supervisors
Examiners
Available from: 2014-04-23 Created: 2013-11-01 Last updated: 2014-04-23Bibliographically approved

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