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Advantages of Monodisperse and Chemically Robust "SpheriCal" Polyester Dendrimers as a "Universal" MS Calibrant
KTH, School of Chemical Science and Engineering (CHE), Fibre and Polymer Technology, Coating Technology.ORCID iD: 0000-0002-9200-8004
2014 (English)In: Journal of the American Society for Mass Spectrometry, ISSN 1044-0305, E-ISSN 1879-1123, Vol. 25, no 3, 303-309 p.Article in journal (Refereed) Published
Abstract [en]

The utilization of dendrimer calibrants as an alternative to peptides and proteins for high mass calibration is explored. These synthetic macromolecules exhibited a number of attractive advantages, including exceptional shelf-lives, broad compatibility with a wide range of matrices and solvents, and evenly spaced calibration masses across the mass range examined, 700-30,000 u. The exceptional purity of these dendrimers and the technical simplicity of this calibration platform validate their broad relevance for high molecular weight mass spectrometry.

Place, publisher, year, edition, pages
2014. Vol. 25, no 3, 303-309 p.
Keyword [en]
Calibrant, Dendrimer, Calibration, Polymer, MALDI-TOF MS
National Category
Biochemistry and Molecular Biology
URN: urn:nbn:se:kth:diva-142867DOI: 10.1007/s13361-013-0777-8ISI: 000330831900002ScopusID: 2-s2.0-84894418871OAI: diva2:704853

QC 20140313

Available from: 2014-03-13 Created: 2014-03-13 Last updated: 2014-03-13Bibliographically approved

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Malkoch, Michael
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