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Effect of hypoxia and bedrest on peripheral vasoconstriction
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2013 (English)In: Proceedings of Life in space for life on earth, 18-22 June 2012, Aberdeen, ESA Communications , 2013, 1-2 p.Conference paper (Refereed)
Abstract [en]

Future planetary habitats may expose astronauts to both microgravity and hypobaric hypoxia, both inducing a reduction in peripheral perfusion. Peripheral temperature changes have been linked to sleep onset and quality [5]. However, it is still unknown what effect combining hypoxia and bedrest has on this relationship. Eleven male participants underwent three 10-day campaigns in a randomized manner: 1) normobaric hypoxic ambulatory confinement (HAmb); 2) normobaric hypoxic bed rest (HBR); 3) normobaric normoxic bed rest (NBR). There was no change in skin temperature gradient between the calf and toes, an index of peripheral perfusion (ΔTc-t), over the 10-d period in the HAmb trial. However, there was a significant increase (p< 0.001) in daytime (9am-9pm) ΔTc-t on day 10 of the inactivity/unloading periods (HBR and NBR trials). This reduction in the perfusion of the toes during the daytime was augmented during the HBR trial compared to NBR (p< 0.001). Before and on day 10 of the interventions we conducted polysomnographic assessment, which revealed no changes in sleep onset and/or architecture. These data support the theory that circadian changes in temperature are functionally linked to sleepiness [1].

Place, publisher, year, edition, pages
ESA Communications , 2013. 1-2 p.
, European Space Agency, (Special Publication) ESA SP, ISSN 0379-6566 ; 706 SP
Keyword [en]
Bed rests, Bedrest, Data support, Hypobaric hypoxias, Planetary habitats, Temperature changes
National Category
Physiology Computer and Information Science
URN: urn:nbn:se:kth:diva-143593ScopusID: 2-s2.0-84892652412ISBN: 978-929092270-4OAI: diva2:707897
Life in Space for Life on Earth; Aberdeen; United Kingdom; 18 June 2012 through 22 June 2012

QC 20140326

Available from: 2014-03-26 Created: 2014-03-25 Last updated: 2014-03-26Bibliographically approved

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