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Electric field Monte Carlo simulation of focused stimulated emission depletion beam, radially and azimuthally polarized beams for in vivo deep bioimaging
KTH, School of Electrical Engineering (EES), Electromagnetic Engineering. KTH, School of Information and Communication Technology (ICT), Centres, Zhejiang-KTH Joint Research Center of Photonics, JORCEP.
2014 (English)In: Journal of Biomedical Optics, ISSN 1083-3668, E-ISSN 1560-2281, Vol. 19, no 1, 011022- p.Article in journal (Refereed) Published
Abstract [en]

An electric field Monte Carlo method is used to study the focal spot of a stimulated emission depletion (STED) beam, radially and azimuthally polarized beams in a turbid medium as a function of the scattering coefficient. To consider the diffraction of light of the wave nature, the wavefront is decomposed into a set of secondary spherical subwaves according to the Huygens principle. From the simulation results, we can find that the STED beam can still form a doughnut focal spot inside the turbid medium. These simulation results are important for the feasibility study of STED microscopy for in vivo deep bioimaging. Similarly, the focal spot for an azimuthally polarized beam can also keep a doughnut spot at the focal plane in a turbid medium.

Place, publisher, year, edition, pages
2014. Vol. 19, no 1, 011022- p.
Keyword [en]
biomedical optics, Monte Carlo, vectorial field, scattering
National Category
Biochemistry and Molecular Biology Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:kth:diva-144133DOI: 10.1117/1.JBO.19.1.011022ISI: 000331892700022Scopus ID: 2-s2.0-84897772730OAI: oai:DiVA.org:kth-144133DiVA: diva2:712104
Note

QC 20140414

Available from: 2014-04-14 Created: 2014-04-10 Last updated: 2017-12-05Bibliographically approved

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He, Sailing
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Electromagnetic EngineeringZhejiang-KTH Joint Research Center of Photonics, JORCEP
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