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Mimicking silk spinning in a microchip
KTH, School of Biotechnology (BIO), Proteomics and Nanobiotechnology.
KTH, School of Biotechnology (BIO), Proteomics and Nanobiotechnology.
2014 (English)In: Sensors and actuators. B, Chemical, ISSN 0925-4005, E-ISSN 1873-3077, Vol. 195, 404-408 p.Article in journal (Refereed) Published
Abstract [en]

Nature's high performance material, spider silk, is formed during the passage of a protein solution through a spinning duct. Herein we present a microfluidic device with dual laminar mobile phases where silk formation can be mimicked and investigated. Recombinant miniature spidroins, with or without the pH-switching N-terminal domain, were used to investigate spinning conditions into silk-like fibers using this setup.

Place, publisher, year, edition, pages
2014. Vol. 195, 404-408 p.
Keyword [en]
Spider silk, Microfluidics, Spinning
National Category
Other Chemistry Topics
Identifiers
URN: urn:nbn:se:kth:diva-144111DOI: 10.1016/j.snb.2014.01.023ISI: 000332417600054Scopus ID: 2-s2.0-84894223458OAI: oai:DiVA.org:kth-144111DiVA: diva2:712171
Funder
Swedish Foundation for Strategic Research Swedish Research Council
Note

QC 20140414

Available from: 2014-04-14 Created: 2014-04-10 Last updated: 2017-12-05Bibliographically approved

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