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A photon-counting silicon-strip detector for digital mammography with an ultrafast 0.18-mu m CMOS ASIC
KTH, School of Engineering Sciences (SCI), Physics, Physics of Medical Imaging.ORCID iD: 0000-0001-8560-3262
KTH, School of Engineering Sciences (SCI), Physics, Physics of Medical Imaging.
KTH, School of Engineering Sciences (SCI), Physics, Physics of Medical Imaging.
KTH, School of Engineering Sciences (SCI), Physics, Physics of Medical Imaging.ORCID iD: 0000-0002-5092-8822
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2014 (English)In: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, ISSN 0168-9002, E-ISSN 1872-9576, Vol. 749, 1-6 p.Article in journal (Refereed) Published
Abstract [en]

We have evaluated a silicon-strip detector with a 0.18-mu m CMOS application specific integrated circuits (ASIC) containing 160 channels for use in photon-counting digital mammography. Measurements were performed at the Elettra light source using monochromatic X-ray beams with different energies and intensities. Energy resolution, Delta E/E-in, was measured to vary between 0.10 and 0.23 in the energy range of 15-40 keV. Pulse pileup has shown little effect on energy resolution.

Place, publisher, year, edition, pages
Elsevier, 2014. Vol. 749, 1-6 p.
Keyword [en]
Mammography, Charge sharing, ASIC, Energy resolution
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:kth:diva-145253DOI: 10.1016/j.nima.2014.02.033ISI: 000334075000001Scopus ID: 2-s2.0-84896521372OAI: oai:DiVA.org:kth-145253DiVA: diva2:717612
Note

QC 20140516

Available from: 2014-05-16 Created: 2014-05-15 Last updated: 2017-12-05Bibliographically approved
In thesis
1. Characterization and Optimization of Silicon-strip Detectors for Mammography and Computed Tomography
Open this publication in new window or tab >>Characterization and Optimization of Silicon-strip Detectors for Mammography and Computed Tomography
2016 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

The goal in medical x-ray imaging is to obtain the image quality requiredfor a given detection task, while ensuring that the patient dose is kept as lowas reasonably achievable. The two most common strategies for dose reductionare: optimizing incident x-ray beams and utilizing energy informationof transmitted beams with new detector techniques (spectral imaging). Inthis thesis, dose optimization schemes were investigated in two x-ray imagingsystems: digital mammography and computed tomography (CT).

In digital mammography, the usefulness of anti-scatter grids was investigatedas a function of breast thickness with varying geometries and experimentalconditions. The general conclusion is that keeping the grid is optimalfor breasts thicker than 5 cm, whereas the dose can be reduced without a gridfor thinner breasts.

A photon-counting silicon-strip detector developed for spectral mammographywas characterized using synchrotron radiation. Energy resolution, ΔE/Ein, was measured to vary between 0.11-0.23 in the energy range 15-40 keV, which is better than the energy resolution of 0.12-0.35 measured inthe state-of-the-art photon-counting mammography system. Pulse pileup hasshown little effect on energy resolution.

In CT, the performance of a segmented silicon-strip detector developedfor spectral CT was evaluated and a theoretical comparison was made withthe state-of-the-art CT detector for some clinically relevant imaging tasks.The results indicate that the proposed photon-counting silicon CT detector issuperior to the state-of-the-art CT detector, especially for high-contrast andhigh-resolution imaging tasks.

The beam quality was optimized for the proposed photon-counting spectralCT detector in two head imaging cases: non-enhanced imaging and Kedgeimaging. For non-enhanced imaging, a 120-kVp spectrum filtered by 2half value layer (HVL) copper (Z = 29) provides the best performance. Wheniodine is used in K-edge imaging, the optimal filter is 2 HVL iodine (Z = 53)and the optimal kVps are 60-75 kVp. In the case of gadolinium imaging, theradiation dose can be minimized at 120 kVp filtered by 2 HVL thulium (Z =69).

Place, publisher, year, edition, pages
STOCKHOLM: KTH Royal Institute of Technology, 2016. viii, 73 p.
Series
TRITA-FYS, ISSN 0280-316X ; 0280-316X
Keyword
mammography, anti-scatter grid, photon-counting, spectral computed tomography, silicon strip, ASIC, energy resolution, Compton scatter, material decomposition, K-edge imaging
National Category
Medical Engineering
Research subject
Medical Technology
Identifiers
urn:nbn:se:kth:diva-184092 (URN)978-91-7595-919-1 (ISBN)
Public defence
2016-04-22, FA 31, ROSLAGSTULLSBACKEN 21, KTH, STOCKHOLM, 09:00 (English)
Opponent
Supervisors
Note

QC 20160401

Available from: 2016-04-01 Created: 2016-03-23 Last updated: 2016-04-01Bibliographically approved

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Chen, HanPersson, Mats

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Chen, HanCederström, BjörnXu, ChengPersson, MatsKarlsson, StaffanDanielsson, Mats
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