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Thiazolidinones Derived from Dynamic Systemic Resolution of Complex Reversible-Reaction Networks
KTH, School of Chemical Science and Engineering (CHE), Chemistry, Organic Chemistry.
KTH, School of Chemical Science and Engineering (CHE), Chemistry, Organic Chemistry.
2014 (English)In: Chemistry - A European Journal, ISSN 0947-6539, E-ISSN 1521-3765, Vol. 20, no 12, 3288-3291 p.Article in journal (Refereed) Published
Abstract [en]

A complex dynamic system based on a network of multiple reversible reactions has been established. The network was applied to a dynamic systemic resolution protocol based on kinetically controlled lipase-catalyzed transformations. This resulted in the formation of cyclized products, where two thiazolidinone compounds were efficiently produced from a range of potential transformations.

Place, publisher, year, edition, pages
2014. Vol. 20, no 12, 3288-3291 p.
Keyword [en]
cyclization, dynamic chemistry, enzymes, lipases, resolution
National Category
Chemical Sciences
Identifiers
URN: urn:nbn:se:kth:diva-146574DOI: 10.1002/chem.201304690ISI: 000332747400006Scopus ID: 2-s2.0-84896403487OAI: oai:DiVA.org:kth-146574DiVA: diva2:724608
Funder
Swedish Research Council
Note

QC 20140613

Available from: 2014-06-13 Created: 2014-06-12 Last updated: 2017-12-05Bibliographically approved

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