The first peripherally masked thiol dendrimers: a facile and highly efficient functionalization strategy of polyester dendrimers via one-pot xanthate deprotection/thiol-acrylate Michael addition reactions
2014 (English)In: Chemical Communications, ISSN 1359-7345, E-ISSN 1364-548X, Vol. 50, no 50, 6574-6577 p.Article in journal (Refereed) Published
Introducing multiple reactive functional groups at the periphery of dendrimer materials presents considerable challenges if the functionality is able to self-react. An efficient and facile approach to introducing masked thiols at the surface of polyester dendrimers is presented. One-pot, deprotection/thiol-acrylate Michael addition from the xanthate-functional dendritic substrates (generation zero to two) has been achieved for the first time, with high efficiency demonstrated using three acrylates of varying chemistry and avoiding disulfide formation.
Place, publisher, year, edition, pages
2014. Vol. 50, no 50, 6574-6577 p.
IdentifiersURN: urn:nbn:se:kth:diva-147441DOI: 10.1039/c3cc49704fISI: 000336837900003ScopusID: 2-s2.0-84901593993OAI: oai:DiVA.org:kth-147441DiVA: diva2:730281
QC 201406272014-06-272014-06-272014-06-27Bibliographically approved