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Dean flow-coupled inertial focusing for ultra-high-throughput particle filtration
KTH, School of Engineering Sciences (SCI), Applied Physics, Cell Physics.
KTH, School of Biotechnology (BIO), Nano Biotechnology (closed 20130101).
KTH, School of Engineering Sciences (SCI), Applied Physics, Cell Physics.
KTH, School of Engineering Sciences (SCI), Applied Physics, Cell Physics.ORCID iD: 0000-0003-0578-4003
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2010 (English)In: 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010: Volume 3, 2010, 1586-1588 p.Conference paper, Published paper (Refereed)
Abstract [en]

Particle manipulation represents an important and fundamental step prior to counting, sorting and detecting bio-particles. In this study, we report dean-coupled inertial focusing of particles in flows through a single curve microchannel at extremely high channel Reynold numbers (∼325). We found the lateral particle focusing position, xf to be fixed and largely independent of radius of curvature and whether particles are pre-focused (at equilibrium) entering the curvature or randomly distributed. Finally, using a single inlet, u-shaped, microchannel we demonstrate filtration of 10μm particles from 2 μm particles at throughputs several orders of magnitude higher than previously shown.

Place, publisher, year, edition, pages
2010. 1586-1588 p.
Keyword [en]
Dean flow, Filtration, Inertial focusing, Micro separation
National Category
Biological Sciences Chemical Sciences
Identifiers
URN: urn:nbn:se:kth:diva-148898Scopus ID: 2-s2.0-84884297718ISBN: 978-161839062-2 (print)OAI: oai:DiVA.org:kth-148898DiVA: diva2:738133
Conference
14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010, 3 October 2010 through 7 October 2010, Groningen, Netherlands
Note

QC 20140815

Available from: 2014-08-15 Created: 2014-08-14 Last updated: 2014-08-15Bibliographically approved

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Brismar, Hjalmar

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Ardabili, SaharGantelius, JesperKowalewski, JacobBrismar, HjalmarRussom, Aman
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