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Extracting quantitative biomechanical parameters for cartilage from second harmonic generation images
KTH, School of Engineering Sciences (SCI), Solid Mechanics (Dept.), Biomechanics. Center of Biomedical Engineering, Institute of Biomechanics, Graz University of Technology, Austria .
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2011 (English)In: Progr. Biomed. Opt. Imaging Proc. SPIE, 2011Conference paper (Refereed)
Abstract [en]

Cartilage from the medial femoral condyle of chicken was sectioned and imaged using second harmonic generation microscopy. Using image analysis techniques based on the Fourier transform we derived quantitative threedimensional data of the fiber direction and dispersion of the collagen fiber network in the superficial layer. These data can be used directly in biomechanical models to enhance the fidelity of these models.

Place, publisher, year, edition, pages
, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, ISSN 1605-7422 ; 7903
Keyword [en]
Biomechanics, Cartilage, Collagen, Constitutive modeling, Nonlinear microscopy, Second harmonic generation, Biomechanical model, Biomechanical parameters, Collagen fiber, Fiber direction, Image analysis techniques, Medial femoral condyle, Second harmonic generation microscopy, Superficial layers, Three-dimensional data, Fourier transforms, Harmonic analysis, Ligaments, Metadata, Nonlinear optics, Harmonic generation
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URN: urn:nbn:se:kth:diva-151226DOI: 10.1117/12.888087ISI: 000297672500068ScopusID: 2-s2.0-79955515901ISBN: 9780819484406OAI: diva2:747736
Multiphoton Microscopy in the Biomedical Sciences XI, 23 January 2011 through 25 January 2011, San Francisco, CA

qc 20140917

Available from: 2014-09-17 Created: 2014-09-15 Last updated: 2014-09-17Bibliographically approved

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Holzapfel, Gerhard
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