Reinforced Degradable Biocomposite by Homogenously Distributed Functionalized Nanodiamond Particles
2015 (English)In: Macromolecular materials and engineering (Print), ISSN 1438-7492, E-ISSN 1439-2054, Vol. 300, no 4, 436-447 p.Article in journal (Refereed) Published
Severe phase separation was observed in blending nanodiamond particle (n-DP) in poly (L-lactide-co-e-caprolactone) (poly(LLA-co-CL)) scaffold. In this study we optimized the scaffold by the addition of 1-50% (w/w) polylactide modified n-DP (n-DP-PLA) or benzoquinone-modified n-DP (n-DP-BQ). Composed by 10% n-DP-PLA, composite had 6 times higher E-modulus in tensile test, whereas the maximum reinforcement can be higher than 15 times. However, n-DP-BQ composites conserved the mechanical properties, and thermal properties of the polymer substrate. The attachment, spreading and growth of UE7T13 cells on modified n-DP composites were similar to poly(LLA-co-CL), and independent to n-DP concentrations. In summary, a proper modified n-DP is the key to reinforce poly(LLA-co-CL) for tissue engineering.
Place, publisher, year, edition, pages
2015. Vol. 300, no 4, 436-447 p.
composites, reinforcement, grafting from, nanodiamond, polylactide
IdentifiersURN: urn:nbn:se:kth:diva-152609DOI: 10.1002/mame.201400387ISI: 000352646000006ScopusID: 2-s2.0-84926514032OAI: oai:DiVA.org:kth-152609DiVA: diva2:750626
FunderEU, FP7, Seventh Framework Programme, 242175
QC 20150508. Updated from manuscript to article in journal.2014-09-292014-09-292015-05-08Bibliographically approved