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A computational framework for patient-specific analysis of articular cartilage incorporating structural information from DT-MRI
KTH, School of Engineering Sciences (SCI), Solid Mechanics (Dept.). Graz University of Technology, Austria.
2009 (English)In: GAMM Mitteilungen, ISSN 0936-7195, Vol. 32, no 2, 157-177 p.Article in journal (Refereed) Published
Abstract [en]

Accurate techniques for simulating soft biological tissue deformation are an increasingly valuable tool in many areas of biomechanical analysis and medical image computing. To model the morphology and the material response of human articular cartilage a phenomenological and patient-specific simulation approach incorporating the collagen fibre fabric is proposed. We then demonstrate a unique combination of ultra-high field Diffusion Tensor Magnetic Resonance Imaging (17.6T DT-MRI) and a novel numerical approach incorporating the empirical data to predict the collagen fibre fabric deformation for an indentation experiment.

Place, publisher, year, edition, pages
2009. Vol. 32, no 2, 157-177 p.
Keyword [en]
Articular cartilage, Collagen fibres, Constitutive modelling, Diffusion tensor, Finite element simulation, Finite viscoelasticity, Indentation test, Magnetic resonance imaging
National Category
Other Medical Sciences
URN: urn:nbn:se:kth:diva-152725DOI: 10.1002/gamm.200910014ScopusID: 2-s2.0-73849105328OAI: diva2:753986

QC 20141009

Available from: 2014-10-09 Created: 2014-10-01 Last updated: 2014-10-09Bibliographically approved

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Holzapfel, Gerhard A.
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