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Optimised synthetic route for tuneable shell Si02@Fe304 core-shell nanoparticles
KTH, School of Information and Communication Technology (ICT), Material Physics (Closed 20120101), Functional Materials, FNM (Closed 20120101).
KTH, School of Information and Communication Technology (ICT), Material Physics (Closed 20120101), Functional Materials, FNM (Closed 20120101).ORCID iD: 0000-0001-5678-5298
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2009 (English)In: Advances in material design for regenerative medicine, drug delivery, and targeting/imaging, Materials Research Society, 2009, 209-214 p.Conference paper, Published paper (Refereed)
Abstract [en]

Multifunctional nanoparticles (that have in their structure different components that can perform various functions) are subject of intensive research activities as they find a large variety of applications in numerous biomedical fields from enhancement of image contrast in MRI to different magnetically controllable drug delivery systems. In this study we report on the synthesis of well-separated, monodisperse single core-shell Si02@Fe304 nanoparticles with an overall diameter of ̃30 nm. The influence of stirring rate and reaction time on synthesis of tuneable shell thickness core-shell nanoparticles is reported. Particles' cell toxicity and performance as MRI contrast agents were also studied due to their promising biological applications (as contrast agents, cell labelling and separation, drug delivery systems, etc.) and results are promising in terms of MRI performance as well as having no significant cytotoxicity.

Place, publisher, year, edition, pages
Materials Research Society, 2009. 209-214 p.
Series
Materials Research Society Symposium Proceedings, ISSN 0272-9172 ; 1140
Keyword [en]
Biological applications, Biomedical fields, Cell labelling, Cell toxicity, Contrast agent, Core-shell, Core-shell nanoparticles, Drug delivery system, Image contrasts, Intensive research, Monodisperse, MRI contrast agents, Multi-functional nanoparticles, Reaction time, Shell thickness, Stirring rates, Synthetic routes, Cytotoxicity, Drug delivery, Nanoparticles, Synthesis (chemical), Shells (structures)
National Category
Polymer Technologies
Identifiers
URN: urn:nbn:se:kth:diva-152735Scopus ID: 2-s2.0-72849118851ISBN: 978-160511112-4 (print)OAI: oai:DiVA.org:kth-152735DiVA: diva2:755391
Conference
MRS Fall Meeting 2008: Advances in Material Design for Regenerative Medicine, Drug Delivery and Targeting/Imaging, 1 December 2008 through 3 December 2008, Boston, MA, United States
Note

QC 20141014

Available from: 2014-10-14 Created: 2014-10-01 Last updated: 2014-10-14Bibliographically approved

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Toprak, Muhammet

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Vogt, Carmen M.Toprak, MuhammetMuhammed, Mamoun
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